| 2. Round | 03/09/2022 | Cañoneros FC | - | Alebrijes de Oaxaca II | 1:3 | ||||
| 4. Round | 10/09/2022 | Cañoneros FC | - | Club de Ciervos | 3:0 |  |
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| 6. Round | 24/09/2022 | Cañoneros FC | - | T'hó Mayas | 3:2 |  |
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| 7. Round | 28/09/2022 | Cañoneros FC | - | Avispones de Chilpancingo | 0:1 | |
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| 8. Round | 01/10/2022 | Huracanes Izcalli | - | Cañoneros FC | 2:2 | ||||
| 9. Round | 08/10/2022 | Cañoneros FC | - | Angelópolis | 3:0 |  |
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| 10. Round | 15/10/2022 | Mazorqueros | - | Cañoneros FC | 3:2 | ||||
| 11. Round | 22/10/2022 | Cañoneros FC | - | Pioneros de Cancún | 2:2 | |
Mexico