| 2. Round | 02/08/2020 | UANL Tigres | - | CF Pachuca | 1:1 | ||||
| 4. Round | 12/08/2020 | UANL Tigres | - | Puebla FC | 2:1 |  |
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| 6. Round | 23/08/2020 | UANL Tigres | - | Pumas UNAM | 1:1 | ||||
| 7. Round | 29/08/2020 | Mazatlán FC | - | UANL Tigres | 1:1 | ||||
| 9. Round | 09/09/2020 | Club León | - | UANL Tigres | 1:1 | ||||
| 10. Round | 13/09/2020 | UANL Tigres | - | Santos Laguna | 2:0 |  |
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| 11. Round | 20/09/2020 | UANL Tigres | - | Gallos Blancos | 3:0 | ||||
| 12. Round | 27/09/2020 | CF Monterrey | - | UANL Tigres | 0:2 | ||||
| 13. Round | 04/10/2020 | UANL Tigres | - | Atlético San Luis | 3:0 | ||||
| 15. Round | 25/10/2020 | UANL Tigres | - | FC Juárez | 1:1 | |
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| 16. Round | 01/11/2020 | CF América | - | UANL Tigres | 3:1 | |
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| 17. Round | 08/11/2020 | UANL Tigres | - | Atlas Guadalajara | 1:1 |
Mexico