| 14. Round | 09/06/2024 | Rhode Island FC | - | Detroit City FC | 0:2 | ||||
| 15. Round | 15/06/2024 | Detroit City FC | - | Charleston Battery | 2:0 | ||||
| 17. Round | 27/06/2024 | Detroit City FC | - | Birmingham Legion | 1:2 | ||||
| 21. Round | 28/07/2024 | Detroit City FC | - | Sacramento Republic | 0:1 | ||||
| 23. Round | 11/08/2024 | Las Vegas Lights FC | - | Detroit City FC | 1:1 | ||||
| 24. Round | 17/08/2024 | Birmingham Legion | - | Detroit City FC | 0:1 | ||||
| 25. Round | 22/08/2024 | Tampa Bay Rowdies | - | Detroit City FC | 2:3 | ||||
| 26. Round | 01/09/2024 | Detroit City FC | - | Hartford Athletic | 1:1 | ||||
| 27. Round | 08/09/2024 | El Paso Locomotive | - | Detroit City FC | 0:0 | ||||
| 28. Round | 15/09/2024 | Detroit City FC | - | New Mexico United | 1:0 | ||||
| 30. Round | 22/09/2024 | Detroit City FC | - | Louisville City FC | 2:1 | ||||
| 35. Round | 27/10/2024 | San Antonio FC | - | Detroit City FC | 1:4 |
Mexico