| 3. Round | 08/08/2020 | Mazatlán FC | - | Deportivo Toluca | 2:1 | ||||
| 4. Round | 11/08/2020 | Club Necaxa | - | Mazatlán FC | 1:0 | ||||
| 12. Round | 26/09/2020 | Deportivo Guadalajara | - | Mazatlán FC | 2:1 | ||||
| 13. Round | 03/10/2020 | Club León | - | Mazatlán FC | 2:1 | ||||
| 14. Round | 17/10/2020 | Mazatlán FC | - | FC Juárez | 3:2 | ||||
| 15. Round | 25/10/2020 | Mazatlán FC | - | CF Monterrey | 1:2 | ||||
| 17. Round | 09/11/2020 | Santos Laguna | - | Mazatlán FC | 4:0 |
Mexico