| Group D | 06/06/2021 | Anguilla | - | Panama | 0:13 |  |
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| Group D | 09/06/2021 | Panama | - | Dom. Republic | 3:0 | |
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| 2. Round | 13/06/2021 | Panama | - | Curaçao | 2:1 | |
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| 2. Round | 16/06/2021 | Curaçao | - | Panama | 0:0 | ||||
| 3. Round | 05/09/2021 | Jamaica | - | Panama | 0:3 | |
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| 3. Round | 13/11/2021 | Honduras | - | Panama | 2:3 | |
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| 3. Round | 17/11/2021 | Panama | - | El Salvador | 2:1 | |
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| 3. Round | 25/03/2022 | Panama | - | Honduras | 1:1 |  |
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| 3. Round | 31/03/2022 | Panama | - | Canada | 1:0 |
Panama