| 1. Round | 05/02/2017 | Club Rubio Ñu | - | Cerro Porteño | 0:3 | ||||
| 2. Round | 11/02/2017 | Club Rubio Ñu | - | Sportivo Trinidense | 1:1 |  |
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| 3. Round | 19/02/2017 | Club Nacional | - | Club Rubio Ñu | 0:3 | ||||
| 4. Round | 24/02/2017 | Club Rubio Ñu | - | Libertad | 0:0 | |
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| 6. Round | 10/03/2017 | Club Rubio Ñu | - | General Díaz | 2:3 | ||||
| 7. Round | 18/03/2017 | Club Olimpia | - | Club Rubio Ñu | 1:1 | ||||
| 9. Round | 29/03/2017 | Independiente CG | - | Club Rubio Ñu | 0:1 | ||||
| 10. Round | 02/04/2017 | Club Rubio Ñu | - | Guaraní | 1:2 | ||||
| 12. Round | 16/04/2017 | Cerro Porteño | - | Club Rubio Ñu | 4:0 | ||||
| 18. Round | 27/05/2017 | Club Rubio Ñu | - | Club Olimpia | 0:1 | ||||
| 19. Round | 02/06/2017 | Sportivo Luqueño | - | Club Rubio Ñu | 1:1 | ||||
| 20. Round | 10/06/2017 | Club Rubio Ñu | - | Independiente CG | 2:2 | |
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| 21. Round | 18/06/2017 | Guaraní | - | Club Rubio Ñu | 2:1 | |
Paraguay