| 3. Round | 29/01/2022 | Gavilanes de Matamoros | - | Mineros de Fresnillo FC | 1:0 | ||||
| 4. Round | 05/02/2022 | Tuzos de la UAZ | - | Gavilanes de Matamoros | 1:1 | ||||
| 5. Round | 12/02/2022 | Gavilanes de Matamoros | - | Alacranes de Durango | 1:1 |  |
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| 7. Round | 26/02/2022 | Gavilanes de Matamoros | - | Saltillo FC | 1:2 |
Mexico