| 4. Round | 21/05/2023 | FC Dallas | - | Houston Dynamo | 1:1 |  |
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| 5. Round | 04/06/2023 | St. Louis City SC | - | Houston Dynamo | 3:0 | ||||
| 5. Round | 11/06/2023 | Houston Dynamo | - | Los Angeles FC | 4:0 | ||||
| 6. Round | 02/07/2023 | Seattle Sounders | - | Houston Dynamo | 1:0 | ||||
| 6. Round | 13/07/2023 | Houston Dynamo | - | Minnesota United FC | 0:3 |
USA