| 4. Round | 27/09/2021 | Al Gharafa | - | Umm-Salal | 1:0 |  |
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| 5. Round | 02/10/2021 | Al Gharafa | - | Qatar SC | 0:2 | ||||
| 6. Round | 17/10/2021 | Al Sadd | - | Al Gharafa | 6:4 | |
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| 7. Round | 26/10/2021 | Al Gharafa | - | Al Khor SC | 5:0 | |
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| 8. Round | 31/10/2021 | Al Gharafa | - | Al Wakrah | 0:1 | ||||
| 9. Round | 03/11/2021 | Al Rayyan | - | Al Gharafa | 0:2 | ||||
| 10. Round | 25/12/2021 | Al Gharafa | - | Al Arabi | 0:0 |  |
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| 11. Round | 29/12/2021 | Al Gharafa | - | Al Sailiya | 3:0 | ||||
| 14. Round | 13/01/2022 | Al Gharafa | - | Al Duhail SC | 2:4 | ||||
| 15. Round | 18/01/2022 | Umm-Salal | - | Al Gharafa | 3:1 | |
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| 16. Round | 23/01/2022 | Qatar SC | - | Al Gharafa | 2:3 | |
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| 17. Round | 05/02/2022 | Al Gharafa | - | Al Sadd | 1:5 | ||||
| 19. Round | 20/02/2022 | Al Wakrah | - | Al Gharafa | 3:2 | ||||
| 20. Round | 24/02/2022 | Al Gharafa | - | Al Rayyan | 3:2 | |
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| 21. Round | 02/03/2022 | Al Arabi | - | Al Gharafa | 3:2 | |
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| 22. Round | 10/03/2022 | Al Sailiya | - | Al Gharafa | 3:2 | |
Mali
