| 4. Round | 29/08/2020 | 9 de Octubre | - | Atlético Santo Domingo | 1:1 | ||||
| 5. Round | 05/09/2020 | Atlético Santo Domingo | - | Independiente Juniors | 0:1 | ||||
| 6. Round | 11/09/2020 | Atlético Santo Domingo | - | América de Quito | 1:0 |  |
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| 7. Round | 16/09/2020 | Chacaritas FC | - | Atlético Santo Domingo | 3:3 | ||||
| 8. Round | 20/09/2020 | Atlético Santo Domingo | - | Atlético Porteño | 0:0 | ||||
| 9. Round | 26/09/2020 | Fuerza Amarilla | - | Atlético Santo Domingo | 0:0 | ||||
| 10. Round | 03/10/2020 | Atlético Santo Domingo | - | Gualaceo SC | 0:1 | ||||
| 11. Round | 11/10/2020 | Manta | - | Atlético Santo Domingo | 1:0 |
Ecuador