| 4. Round | 30/01/2011 | Monarcas Morelia | - | Club San Luis | 3:3 | ||||
| 14. Round | 03/02/2011 | CF América | - | Club San Luis | 3:0 | ||||
| 13. Round | 10/04/2011 | Club San Luis | - | Club Necaxa | 0:0 | ||||
| 15. Round | 17/04/2011 | Club San Luis | - | Deportivo Toluca | 1:2 | ||||
| 16. Round | 24/04/2011 | Santos Laguna | - | Club San Luis | 1:3 |  |
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| 17. Round | 01/05/2011 | Club San Luis | - | Cruz Azul | 0:0 |
Mexico