| 5. Round | 13/08/2011 | Club San Luis | - | CF Monterrey | 1:0 |  |
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| 6. Round | 21/08/2011 | UANL Tigres | - | Club San Luis | 1:0 |  |
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| 7. Round | 28/08/2011 | Club San Luis | - | Deportivo Guadalajara | 2:0 | ||||
| 3. Round | 04/09/2011 | Club San Luis | - | Monarcas Morelia | 2:3 | ||||
| 8. Round | 11/09/2011 | Atlas Guadalajara | - | Club San Luis | 1:1 | ||||
| 4. Round | 15/09/2011 | CF América | - | Club San Luis | 2:2 | |
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| 9. Round | 18/09/2011 | Club San Luis | - | Santos Laguna | 0:1 | ||||
| 11. Round | 02/10/2011 | Club San Luis | - | Puebla FC | 2:1 | ||||
| 12. Round | 09/10/2011 | Atlante | - | Club San Luis | 1:1 |  |
Mexico