| 4. Round | 02/02/2025 | Gavilanes de Matamoros | - | Colima FC | 6:1 | ||||
| 5. Round | 08/02/2025 | Colima FC | - | Aguacateros de Peribán | 0:4 | ||||
| 6. Round | 15/02/2025 | Club Zacatepec | - | Colima FC | 2:0 |  |
|||
| 9. Round | 08/03/2025 | Colima FC | - | Reboceros de La Piedad | 2:1 | ||||
| 10. Round | 15/03/2025 | Aguacateros CDU | - | Colima FC | 2:0 | ||||
| 11. Round | 22/03/2025 | Colima FC | - | Correcaminos UAT II | 1:2 | ||||
| 13. Round | 05/04/2025 | Leones Negros II | - | Colima FC | 2:0 |
Mexico