| 5. Round | 09/02/2020 | Always Ready | - | Real Santa Cruz | 6:0 | ||||
| 8. Round | 22/02/2020 | Atlético Palmaflor | - | Real Santa Cruz | 2:1 |  |
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| 9. Round | 27/02/2020 | Real Santa Cruz | - | Bolívar | 2:4 | |
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| 10. Round | 03/03/2020 | Royal Pari | - | Real Santa Cruz | 0:2 | ||||
| 11. Round | 06/03/2020 | Real Santa Cruz | - | Nacional Potosí | 2:1 | |
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| 12. Round | 15/03/2020 | CD Guabirá | - | Real Santa Cruz | 1:0 | |
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| 13. Round | 27/11/2020 | Real Santa Cruz | - | Club Aurora | 4:2 | |
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| 15. Round | 02/12/2020 | The Strongest | - | Real Santa Cruz | 4:2 | |
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| 20. Round | 16/12/2020 | Oriente Petrolero | - | Real Santa Cruz | 3:2 | ||||
| 21. Round | 19/12/2020 | Real Santa Cruz | - | Atlético Palmaflor | 2:1 | |
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| 22. Round | 22/12/2020 | Bolívar | - | Real Santa Cruz | 4:0 |
Bolivia