| 22. Round | 26/09/2021 | Everton | - | Curicó Unido | 0:0 | ||||
| 23. Round | 28/09/2021 | La Serena | - | Everton | 0:2 |  |
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| 25. Round | 09/10/2021 | Everton | - | Universidad de Chile | 1:0 | |
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| 26. Round | 16/10/2021 | Santiago Wanderers | - | Everton | 2:1 | ||||
| 28. Round | 23/10/2021 | Ñublense | - | Everton | 1:1 | ||||
| 29. Round | 30/10/2021 | Unión Española | - | Everton | 3:2 | ||||
| 30. Round | 03/11/2021 | Everton | - | Audax Italiano | 1:2 | ||||
| 31. Round | 07/11/2021 | Cobresal | - | Everton | 2:2 | ||||
| 32. Round | 14/11/2021 | Everton | - | Unión La Calera | 1:2 | |
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| 33. Round | 27/11/2021 | Deportes Melipilla | - | Everton | 1:0 | |
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| 34. Round | 04/12/2021 | Everton | - | Universidad Católica | 0:3 |
Colombia