| 7. Round | 29/02/2020 | River Plate | - | 12 de Octubre de Itauguá | 0:2 | ||||
| 9. Round | 21/07/2020 | River Plate | - | Club Nacional | 1:1 | ||||
| 10. Round | 25/07/2020 | River Plate | - | Cerro Porteño | 0:2 | ||||
| 11. Round | 31/07/2020 | Sportivo Luqueño | - | River Plate | 0:1 | ||||
| 6. Round | 05/08/2020 | Guaraní | - | River Plate | 3:0 | ||||
| 12. Round | 09/08/2020 | Sol de América | - | River Plate | 0:0 | ||||
| 14. Round | 16/08/2020 | General Díaz | - | River Plate | 2:1 |  |
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| 15. Round | 23/08/2020 | River Plate | - | Libertad | 1:2 | ||||
| 16. Round | 26/08/2020 | San Lorenzo | - | River Plate | 0:0 | ||||
| 17. Round | 29/08/2020 | River Plate | - | Guaraní | 1:0 | ||||
| 18. Round | 04/09/2020 | 12 de Octubre de Itauguá | - | River Plate | 0:1 | ||||
| 19. Round | 12/09/2020 | River Plate | - | Club Olimpia | 0:4 | ||||
| 20. Round | 22/09/2020 | Club Nacional | - | River Plate | 1:2 |
Paraguay