| 1. Round | 12/04/2021 | Universidad de Concepción | - | Santiago Morning | 3:3 | ||||
| 2. Round | 19/04/2021 | Santiago Morning | - | CD Magallanes | 1:2 | ||||
| 3. Round | 26/04/2021 | Santiago Morning | - | Santa Cruz | 1:3 |  |
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| 4. Round | 03/05/2021 | Deportes Copiapó | - | Santiago Morning | 2:2 | ||||
| 15. Round | 15/08/2021 | Deportes Temuco | - | Santiago Morning | 0:2 | ||||
| 17. Round | 27/08/2021 | CD Magallanes | - | Santiago Morning | 0:1 | ||||
| 19. Round | 08/09/2021 | Santiago Morning | - | Deportes Copiapó | 2:3 | ||||
| 20. Round | 16/09/2021 | San Marcos | - | Santiago Morning | 4:0 | ||||
| 21. Round | 22/09/2021 | Santiago Morning | - | Cobreloa | 2:1 | |
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| 22. Round | 27/09/2021 | Rangers | - | Santiago Morning | 0:1 | ||||
| 23. Round | 03/10/2021 | Santiago Morning | - | Fernández Vial | 2:2 |  |
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| 28. Round | 01/11/2021 | Santiago Morning | - | Unión San Felipe | 1:0 | ||||
| 29. Round | 05/11/2021 | Puerto Montt | - | Santiago Morning | 0:0 |
Chile