| 1. Round | 10/02/2023 | Cobreloa | - | San Marcos | 2:1 |  |
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| 2. Round | 17/02/2023 | San Marcos | - | Deportes Iquique | 2:3 | ||||
| 3. Round | 28/02/2023 | Santiago Morning | - | San Marcos | 2:1 | ||||
| 4. Round | 04/03/2023 | San Marcos | - | Unión San Felipe | 0:2 | ||||
| 7. Round | 27/03/2023 | Rangers | - | San Marcos | 4:2 | ||||
| 8. Round | 17/04/2023 | San Marcos | - | La Serena | 2:1 | ||||
| 9. Round | 23/04/2023 | Deportes Temuco | - | San Marcos | 1:1 | |
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| 11. Round | 10/05/2023 | Santiago Wanderers | - | San Marcos | 1:1 | ||||
| 14. Round | 28/05/2023 | Antofagasta | - | San Marcos | 4:1 | ||||
| 15. Round | 02/06/2023 | San Marcos | - | Barnechea | 3:1 | |
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| 17. Round | 08/07/2023 | Deportes Iquique | - | San Marcos | 2:1 | ||||
| 18. Round | 16/07/2023 | San Marcos | - | Santiago Morning | 2:2 | ||||
| 25. Round | 04/09/2023 | Universidad de Concepción | - | San Marcos | 2:1 | ||||
| 27. Round | 24/09/2023 | Puerto Montt | - | San Marcos | 1:1 | |
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| 28. Round | 03/10/2023 | San Marcos | - | Santa Cruz | 3:2 | ||||
| 29. Round | 09/10/2023 | San Marcos | - | Antofagasta | 4:3 | ||||
| 30. Round | 14/10/2023 | Barnechea | - | San Marcos | 3:3 |
Chile