| 2. Round | 01/03/2020 | Cobreloa | - | San Marcos | 3:1 |  |
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| 3. Round | 07/03/2020 | San Marcos | - | Deportes Melipilla | 1:0 | ||||
| 4. Round | 16/03/2020 | Deportes Temuco | - | San Marcos | 2:1 | |
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| 5. Round | 29/08/2020 | Ñublense | - | San Marcos | 1:0 | ||||
| 6. Round | 03/09/2020 | San Luis | - | San Marcos | 1:2 | ||||
| 7. Round | 09/09/2020 | Barnechea | - | San Marcos | 2:1 | ||||
| 11. Round | 27/09/2020 | Rangers | - | San Marcos | 1:2 | ||||
| 12. Round | 30/09/2020 | San Marcos | - | Deportes Valdivia | 1:1 | ||||
| 13. Round | 05/10/2020 | Unión San Felipe | - | San Marcos | 1:0 | |
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| 14. Round | 08/10/2020 | San Marcos | - | Santa Cruz | 2:1 | ||||
| 15. Round | 12/10/2020 | Puerto Montt | - | San Marcos | 3:0 | ||||
| 16. Round | 28/10/2020 | San Marcos | - | Deportes Temuco | 1:0 | ||||
| 28. Round | 29/12/2020 | San Marcos | - | Barnechea | 1:0 | ||||
| 20. Round | 03/01/2021 | San Marcos | - | Deportes Copiapó | 2:3 | |
Chile