| 2. Round | 08/05/2021 | New York RB II | - | Charleston Battery | 1:1 | ||||
| 2. Round | 15/05/2021 | New York RB II | - | Miami FC | 0:1 | ||||
| 2. Round | 19/05/2021 | Loudoun United | - | New York RB II | 1:2 | ||||
| 2. Round | 23/05/2021 | Charleston Battery | - | New York RB II | 2:2 | ||||
| 2. Round | 29/05/2021 | New York RB II | - | Pittsburgh Riverhounds | 0:3 | ||||
| 6. Round | 01/09/2021 | Pittsburgh Riverhounds | - | New York RB II | 1:0 | ||||
| 6. Round | 05/09/2021 | New York RB II | - | Hartford Athletic | 2:0 | ||||
| 6. Round | 19/09/2021 | New York RB II | - | Memphis 901 | 0:3 | ||||
| 6. Round | 23/09/2021 | Charleston Battery | - | New York RB II | 2:3 | ||||
| 6. Round | 27/09/2021 | Real Monarchs SLC | - | New York RB II | 0:0 | ||||
| 7. Round | 16/10/2021 | Tampa Bay Rowdies | - | New York RB II | 1:1 | ||||
| 7. Round | 21/10/2021 | New York RB II | - | Loudoun United | 3:0 | ||||
| 7. Round | 25/10/2021 | Miami FC | - | New York RB II | 2:0 | ||||
| 7. Round | 30/10/2021 | Loudoun United | - | New York RB II | 1:4 |
USA