| 20. Round | 11/09/2010 | Zenit St. Petersburg | - | FK Tom Tomsk | 2:0 | ||||
| 21. Round | 19/09/2010 | FK Tom Tomsk | - | Lokomotiv Moskva | 1:1 | ||||
| 22. Round | 26/09/2010 | FK Tom Tomsk | - | CSKA Moskva | 0:3 | ||||
| 23. Round | 02/10/2010 | Terek Grozny | - | FK Tom Tomsk | 1:0 | ||||
| 24. Round | 16/10/2010 | FK Tom Tomsk | - | FK Saturn | 2:2 | ||||
| 26. Round | 31/10/2010 | FK Tom Tomsk | - | FK Amkar Perm | 1:0 | ||||
| 28. Round | 13/11/2010 | FK Tom Tomsk | - | Spartak Vladikavkaz | 1:1 |
Japan