| 2. Round | 25/08/2020 | Club León [Women] | - | CF Pachuca [Women] | 1:2 | ||||
| 4. Round | 08/09/2020 | Club León [Women] | - | FC Juárez [Women] | 1:0 | ||||
| 8. Round | 29/09/2020 | Club León [Women] | - | Atlas Guadalajara [Women] | 1:5 | ||||
| 10. Round | 09/10/2020 | Club Necaxa [Women] | - | Club León [Women] | 2:1 |  |
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| 13. Round | 29/10/2020 | Club León [Women] | - | Gallos Blancos [Women] | 1:3 | ||||
| 14. Round | 06/11/2020 | Atlético San Luis [Women] | - | Club León [Women] | 2:1 | ||||
| 15. Round | 10/11/2020 | Club León [Women] | - | Cruz Azul [Women] | 1:1 | ||||
| 16. Round | 15/11/2020 | Deportivo Toluca [Women] | - | Club León [Women] | 1:3 | ||||
| 17. Round | 19/11/2020 | Club León [Women] | - | Pumas UNAM [Women] | 3:2 |
Mexico