| 1. Round | 17/07/2018 | Deportivo Guadalajara [Women] | - | Club León [Women] | 1:0 | ||||
| 2. Round | 21/07/2018 | Atlas Guadalajara [Women] | - | Deportivo Guadalajara [Women] | 0:2 | ||||
| 3. Round | 29/07/2018 | Deportivo Guadalajara [Women] | - | Santos Laguna [Women] | 3:1 |  |
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| 4. Round | 07/08/2018 | CF Monterrey [Women] | - | Deportivo Guadalajara [Women] | 0:0 | ||||
| 5. Round | 13/08/2018 | Deportivo Guadalajara [Women] | - | Club Necaxa [Women] | 1:0 | ||||
| 6. Round | 20/08/2018 | Monarcas Morelia [Women] | - | Deportivo Guadalajara [Women] | 1:5 | |
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| 9. Round | 13/09/2018 | Gallos Blancos [Women] | - | Deportivo Guadalajara [Women] | 0:0 | ||||
| 10. Round | 18/09/2018 | Club León [Women] | - | Deportivo Guadalajara [Women] | 3:5 | |
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| 12. Round | 02/10/2018 | Santos Laguna [Women] | - | Deportivo Guadalajara [Women] | 1:3 | ||||
| 14. Round | 19/10/2018 | Club Necaxa [Women] | - | Deportivo Guadalajara [Women] | 0:3 |
Mexico