| 1. Round | 12/02/2021 | Unión de Santa Fe II | - | Atlético Tucumán II | 2:1 | ||||
| 2. Round | 19/02/2021 | Atlético Tucumán II | - | Central Córdoba SdE II | 2:0 | ||||
| 3. Round | 26/02/2021 | Atlético Tucumán II | - | Huracán II | 1:2 | ||||
| 4. Round | 05/03/2021 | Lanús II | - | Atlético Tucumán II | 2:3 | ||||
| 5. Round | 12/03/2021 | Atlético Tucumán II | - | Patronato de Paraná II | 2:2 | ||||
| 6. Round | 19/03/2021 | Gimnasia de La Plata II | - | Atlético Tucumán II | 0:0 | ||||
| 8. Round | 02/04/2021 | Sarmiento de Junín II | - | Atlético Tucumán II | 4:2 | ||||
| 12. Round | 30/04/2021 | Independiente II | - | Atlético Tucumán II | 1:0 | ||||
| 13. Round | 07/05/2021 | Atlético Tucumán II | - | Defensa y Justicia II | 3:4 |
Argentina