| 4. Round | 22/07/2022 | Club Necaxa [U20] | - | FC Juárez [U20] | 1:2 | ||||
| 5. Round | 27/07/2022 | Club Necaxa [U20] | - | CF Pachuca [U20] | 0:1 | ||||
| 6. Round | 30/07/2022 | Cruz Azul [U20] | - | Club Necaxa [U20] | 2:0 | ||||
| 7. Round | 07/08/2022 | Atlético San Luis [U20] | - | Club Necaxa [U20] | 2:2 |  |
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| 8. Round | 12/08/2022 | Club Necaxa [U20] | - | CF Monterrey [U20] | 2:1 | ||||
| 12. Round | 02/09/2022 | Club Necaxa [U20] | - | Club León [U20] | 2:2 | ||||
| 13. Round | 06/09/2022 | Santos Laguna [U20] | - | Club Necaxa [U20] | 3:2 | ||||
| 14. Round | 10/09/2022 | Club Necaxa [U20] | - | CF América [U20] | 1:2 |
Mexico