| 3. Round | 24/07/2021 | FK Krasnodar 2 | - | Tekstilshchik Ivanovo | 1:1 | ||||
| 4. Round | 31/07/2021 | FK Krasnodar 2 | - | Olimp-Dolgoprudny | 2:0 | ||||
| 5. Round | 08/08/2021 | SKA-Khabarovsk | - | FK Krasnodar 2 | 1:0 | ||||
| 7. Round | 21/08/2021 | Metallurg Lipetsk | - | FK Krasnodar 2 | 1:2 | ||||
| 9. Round | 05/09/2021 | Fakel Voronezh | - | FK Krasnodar 2 | 0:0 | ||||
| 10. Round | 11/09/2021 | FK Krasnodar 2 | - | FK Tom Tomsk | 2:1 | ||||
| 11. Round | 15/09/2021 | FK Orenburg | - | FK Krasnodar 2 | 2:0 |
Russia