| 6. Round | 02/10/2010 | Defensor Sporting | - | Bella Vista | 1:2 | ||||
| 3. Round | 06/10/2010 | Defensor Sporting | - | CA Cerro | 2:0 | ||||
| 7. Round | 09/10/2010 | Miramar Misiones | - | Defensor Sporting | 0:1 | ||||
| 5. Round | 12/10/2010 | Defensor Sporting | - | El Tanque Sisley | 3:1 | ||||
| 8. Round | 16/10/2010 | Danubio | - | Defensor Sporting | 1:1 |  |
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| 15. Round | 05/12/2010 | Tacuarembó | - | Defensor Sporting | 1:3 |
Uruguay