| 6. Round | 19/08/2012 | D.C. United | - | Philadelphia Union | 1:1 | ||||
| 6. Round | 25/08/2012 | Philadelphia Union | - | Real Salt Lake | 0:0 | ||||
| 6. Round | 30/08/2012 | Philadelphia Union | - | Columbus Crew | 1:2 | ||||
| 7. Round | 02/09/2012 | New England Revolution | - | Philadelphia Union | 0:0 | ||||
| 7. Round | 15/09/2012 | Toronto FC | - | Philadelphia Union | 1:1 | ||||
| 7. Round | 21/09/2012 | Philadelphia Union | - | D.C. United | 0:1 | ||||
| 7. Round | 23/09/2012 | Philadelphia Union | - | Houston Dynamo | 3:1 | ||||
| 7. Round | 30/09/2012 | Columbus Crew | - | Philadelphia Union | 3:2 |  |
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| 8. Round | 04/10/2012 | Chicago Fire | - | Philadelphia Union | 1:3 | ||||
| 8. Round | 21/10/2012 | Houston Dynamo | - | Philadelphia Union | 3:1 | ||||
| 8. Round | 25/10/2012 | Sporting Kansas City | - | Philadelphia Union | 2:1 | ||||
| 8. Round | 27/10/2012 | Philadelphia Union | - | New York RB | 0:3 |
USA