| 8. Round | 03/10/2010 | FC Twente | - | FC Groningen | 4:2 |  |
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| 9. Round | 17/10/2010 | FC Groningen | - | sc Heerenveen | 1:0 | ||||
| 11. Round | 27/10/2010 | FC Groningen | - | ADO Den Haag | 3:1 | ||||
| 18. Round | 12/12/2010 | FC Groningen | - | AZ Alkmaar | 2:0 | ||||
| 22. Round | 06/02/2011 | FC Groningen | - | Willem II | 7:1 | ||||
| 26. Round | 06/03/2011 | FC Groningen | - | Heracles Almelo | 1:4 |
Netherlands