| 5. Round | 15/08/2021 | Olimpija Ljubljana | - | FC Koper | 1:3 | ||||
| 6. Round | 21/08/2021 | FC Koper | - | NK Maribor | 2:0 | ||||
| 8. Round | 12/09/2021 | NK Radomlje | - | FC Koper | 1:4 | ||||
| 9. Round | 19/09/2021 | FC Koper | - | NK Bravo | 0:1 | ||||
| 10. Round | 23/09/2021 | FC Koper | - | NK Aluminij | 1:3 | ||||
| 11. Round | 26/09/2021 | NŠ Mura | - | FC Koper | 0:0 | ||||
| 4. Round | 29/09/2021 | FC Koper | - | NK Domžale | 4:2 | ||||
| 12. Round | 03/10/2021 | FC Koper | - | NK Celje | 2:2 | ||||
| 16. Round | 06/11/2021 | FC Koper | - | NK Tabor Sežana | 1:0 | ||||
| 17. Round | 21/11/2021 | FC Koper | - | NK Radomlje | 3:2 | ||||
| 18. Round | 28/11/2021 | NK Bravo | - | FC Koper | 1:2 | ||||
| 19. Round | 04/12/2021 | NK Aluminij | - | FC Koper | 1:1 | ||||
| 20. Round | 12/12/2021 | FC Koper | - | NŠ Mura | 2:2 |
Slovenia