| 1. Round | 16/01/2022 | Montañeses FC | - | Deportivo Dongu | 3:0 | ||||
| 3. Round | 29/01/2022 | Sporting Canamy | - | Deportivo Dongu | 2:1 | ||||
| 4. Round | 05/02/2022 | Deportivo Dongu | - | Yalmakan FC | 0:2 | ||||
| 5. Round | 13/02/2022 | Lobos ULMX | - | Deportivo Dongu | 2:0 | ||||
| 6. Round | 19/02/2022 | Deportivo Dongu | - | Reboceros de La Piedad | 0:4 | ||||
| 7. Round | 26/02/2022 | Deportivo Dongu | - | Inter Playa | 1:4 | ||||
| 8. Round | 05/03/2022 | Cañoneros FC | - | Deportivo Dongu | 1:0 |
Mexico