| 1. Round | 21/07/2018 | Cruz Azul [U20] | - | Puebla FC [U20] | 1:2 | ||||
| 2. Round | 27/07/2018 | Puebla FC [U20] | - | Deportivo Toluca [U20] | 0:0 | ||||
| 4. Round | 10/08/2018 | Puebla FC [U20] | - | CD Veracruz [U20] | 1:1 | ||||
| 6. Round | 21/08/2018 | Puebla FC [U20] | - | Atlas Guadalajara [U20] | 1:2 | ||||
| 7. Round | 25/08/2018 | CF Pachuca [U20] | - | Puebla FC [U20] | 3:2 | ||||
| 8. Round | 31/08/2018 | Puebla FC [U20] | - | CF Monterrey [U20] | 1:1 | ||||
| 3. Round | 08/09/2018 | Santos Laguna [U20] | - | Puebla FC [U20] | 2:3 | ||||
| 9. Round | 15/09/2018 | Gallos Blancos [U20] | - | Puebla FC [U20] | 3:0 | ||||
| 10. Round | 21/09/2018 | Puebla FC [U20] | - | CF América [U20] | 0:1 | ||||
| 11. Round | 30/09/2018 | Pumas UNAM [U20] | - | Puebla FC [U20] | 2:0 | ||||
| 12. Round | 07/10/2018 | Puebla FC [U20] | - | Lobos BUAP [U20] | 3:2 | ||||
| 13. Round | 21/10/2018 | Monarcas Morelia [U20] | - | Puebla FC [U20] | 1:0 | ||||
| 16. Round | 10/11/2018 | UANL Tigres [U20] | - | Puebla FC [U20] | 1:2 |
Mexico