| 1. Round | 20/07/2021 | FC Juárez [Women] | - | Cruz Azul [Women] | 0:1 | ||||
| 2. Round | 25/07/2021 | CF Monterrey [Women] | - | FC Juárez [Women] | 2:0 | ||||
| 5. Round | 14/08/2021 | Deportivo Toluca [Women] | - | FC Juárez [Women] | 1:1 | ||||
| 7. Round | 31/08/2021 | FC Juárez [Women] | - | Club León [Women] | 0:2 | ||||
| 8. Round | 04/09/2021 | Mazatlán FC [Women] | - | FC Juárez [Women] | 1:2 | ||||
| 9. Round | 12/09/2021 | FC Juárez [Women] | - | CF América [Women] | 1:1 | ||||
| 10. Round | 28/09/2021 | Pumas UNAM [Women] | - | FC Juárez [Women] | 3:0 | ||||
| 13. Round | 19/10/2021 | FC Juárez [Women] | - | CF Pachuca [Women] | 1:3 | ||||
| 14. Round | 02/11/2021 | UANL Tigres [Women] | - | FC Juárez [Women] | 3:0 | ||||
| 15. Round | 09/11/2021 | FC Juárez [Women] | - | Puebla FC [Women] | 1:2 |
Mexico