| 1. Round | 19/03/2022 | Dinamo Brest | - | Shakhter Soligorsk | 1:1 |  |
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| 2. Round | 03/04/2022 | Shakhter Soligorsk | - | Dnepr Mogilev | 4:0 | |
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| 3. Round | 10/04/2022 | FK Isloch Minsk | - | Shakhter Soligorsk | 1:1 | |
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| 4. Round | 16/04/2022 | Shakhter Soligorsk | - | BATE Borisov | 0:1 |  |
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| 5. Round | 22/04/2022 | Neman Grodno | - | Shakhter Soligorsk | 1:1 | ||||
| 6. Round | 02/05/2022 | Shakhter Soligorsk | - | FK Gomel | 1:0 | |
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| 7. Round | 08/05/2022 | Energetik-BGU Minsk | - | Shakhter Soligorsk | 0:1 | ||||
| 8. Round | 14/05/2022 | Shakhter Soligorsk | - | Dinamo Minsk | 1:0 | |
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| 9. Round | 20/05/2022 | FK Minsk | - | Shakhter Soligorsk | 1:0 | ||||
| 10. Round | 28/05/2022 | Shakhter Soligorsk | - | FK Vitebsk | 2:0 | |
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| 12. Round | 25/06/2022 | Shakhter Soligorsk | - | Torpedo-BelAZ Zhodino | 0:1 |
Gambia