| 3. Round | 25/05/2022 | New Mexico United | - | Phoenix Rising | 7:0 | ||||
| 4. Round | 05/06/2022 | Orange County SC | - | New Mexico United | 1:2 |  |
|||
| 5. Round | 14/07/2022 | FC Tulsa | - | New Mexico United | 1:2 | ||||
| 5. Round | 24/07/2022 | Detroit City FC | - | New Mexico United | 2:2 | ||||
| 6. Round | 18/08/2022 | New Mexico United | - | Memphis 901 | 0:2 | ||||
| 6. Round | 21/08/2022 | New Mexico United | - | Monterey Bay FC | 2:0 | ||||
| 6. Round | 28/08/2022 | Colorado Springs Switchbacks | - | New Mexico United | 1:0 | ||||
| 7. Round | 03/09/2022 | New Mexico United | - | El Paso Locomotive | 1:2 | ||||
| 7. Round | 11/09/2022 | Rio Grande Valley FC | - | New Mexico United | 3:1 | ||||
| 8. Round | 09/10/2022 | San Diego Loyal | - | New Mexico United | 3:3 | ||||
| 8. Round | 13/10/2022 | New Mexico United | - | Los Angeles Galaxy II | 3:2 | ||||
| 8. Round | 16/10/2022 | New Mexico United | - | Colorado Springs Switchbacks | 2:0 |
USA