| 2. Round | 15/01/2021 | FC Juárez [U17] | - | Club Tijuana [U17] | 3:0 | ||||
| 3. Round | 22/01/2021 | Puebla FC [U17] | - | Club Tijuana [U17] | 1:3 | ||||
| 4. Round | 30/01/2021 | Club Tijuana [U17] | - | Deportivo Toluca [U17] | 2:3 |  |
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| 5. Round | 04/02/2021 | Atlético San Luis [U17] | - | Club Tijuana [U17] | 1:1 | ||||
| 7. Round | 21/02/2021 | UANL Tigres [U17] | - | Club Tijuana [U17] | 1:0 | ||||
| 8. Round | 28/02/2021 | CF Monterrey [U17] | - | Club Tijuana [U17] | 3:2 | ||||
| 9. Round | 03/03/2021 | Club Tijuana [U17] | - | CF América [U17] | 4:0 | |
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| 10. Round | 08/03/2021 | CF Pachuca [U17] | - | Club Tijuana [U17] | 3:0 | ||||
| 12. Round | 20/03/2021 | Club Tijuana [U17] | - | Gallos Blancos [U17] | 3:2 | ||||
| 17. Round | 01/05/2021 | Cruz Azul [U17] | - | Club Tijuana [U17] | 1:0 |
USA