| 1. Round | 22/07/2017 | Libertad | - | Club Rubio Ñu | 0:0 |  |
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| 4. Round | 12/08/2017 | Club Rubio Ñu | - | Club Nacional | 0:1 | |
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| 5. Round | 20/08/2017 | Sol de América | - | Club Rubio Ñu | 1:2 | |
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| 6. Round | 27/08/2017 | Sportivo Luqueño | - | Club Rubio Ñu | 3:0 | |
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| 7. Round | 01/09/2017 | Club Rubio Ñu | - | Guaraní | 0:1 | ||||
| 8. Round | 09/09/2017 | Cerro Porteño | - | Club Rubio Ñu | 1:0 | |
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| 10. Round | 23/09/2017 | Sportivo Trinidense | - | Club Rubio Ñu | 0:1 | ||||
| 11. Round | 29/09/2017 | Club Rubio Ñu | - | Independiente CG | 0:1 | |
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| 13. Round | 16/10/2017 | Deportivo Capiatá | - | Club Rubio Ñu | 1:2 | ||||
| 15. Round | 22/10/2017 | Club Nacional | - | Club Rubio Ñu | 1:1 | ||||
| 20. Round | 27/11/2017 | General Díaz | - | Club Rubio Ñu | 0:0 |
Paraguay