| 1. Round | 05/02/2017 | Club Nacional | - | Deportivo Capiatá | 1:2 | ||||
| 2. Round | 12/02/2017 | Cerro Porteño | - | Club Nacional | 2:1 | ||||
| 3. Round | 19/02/2017 | Club Nacional | - | Club Rubio Ñu | 0:3 | ||||
| 4. Round | 25/02/2017 | Club Nacional | - | Sportivo Trinidense | 1:1 | ||||
| 5. Round | 03/03/2017 | Libertad | - | Club Nacional | 1:1 | ||||
| 6. Round | 11/03/2017 | Club Nacional | - | Sol de América | 1:1 | ||||
| 7. Round | 17/03/2017 | General Díaz | - | Club Nacional | 1:1 | ||||
| 8. Round | 25/03/2017 | Club Nacional | - | Club Olimpia | 2:4 | ||||
| 19. Round | 04/06/2017 | Club Olimpia | - | Club Nacional | 0:0 |
Paraguay