| 3. Round | 12/09/2009 | Cerro Largo | - | Central Español | 1:0 | ||||
| 4. Round | 20/09/2009 | Central Español | - | Defensor Sporting | 0:4 | ||||
| 5. Round | 27/09/2009 | CA Cerro | - | Central Español | 1:2 | ||||
| 6. Round | 03/10/2009 | Central Español | - | Montevideo Wanderers | 1:1 | ||||
| 7. Round | 17/10/2009 | Tacuarembó | - | Central Español | 3:1 |  |
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| 8. Round | 23/10/2009 | Central Español | - | Peñarol | 2:3 | ||||
| 9. Round | 28/10/2009 | Nacional | - | Central Español | 5:1 | ||||
| 10. Round | 01/11/2009 | Central Español | - | Liverpool | 0:0 | ||||
| 11. Round | 07/11/2009 | Atenas | - | Central Español | 0:0 | ||||
| 12. Round | 22/11/2009 | Central Español | - | Cerrito | 2:2 | |
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| 13. Round | 05/12/2009 | Danubio | - | Central Español | 2:0 |  |
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| 14. Round | 09/12/2009 | Central Español | - | Rampla Juniors | 0:3 | ||||
| 15. Round | 13/12/2009 | Central Español | - | Fénix | 1:0 |
Uruguay