| 2. Round | 01/09/2012 | Danubio | - | Progreso | 1:4 | ||||
| 1. Round | 09/09/2012 | Danubio | - | Liverpool | 2:2 | ||||
| 3. Round | 16/09/2012 | Danubio | - | Montevideo Wanderers | 2:4 | ||||
| 4. Round | 23/09/2012 | Juventud de Las Piedras | - | Danubio | 0:0 | ||||
| 5. Round | 30/09/2012 | Danubio | - | Peñarol | 0:0 | ||||
| 6. Round | 07/10/2012 | Nacional | - | Danubio | 2:1 |  |
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| 8. Round | 21/10/2012 | Defensor Sporting | - | Danubio | 3:1 |
Uruguay