| 2. Round | 26/02/2012 | Defensor Sporting | - | Nacional | 2:2 | ||||
| 3. Round | 04/03/2012 | Cerrito | - | Defensor Sporting | 0:2 | ||||
| 5. Round | 24/03/2012 | Fénix | - | Defensor Sporting | 0:1 | ||||
| 6. Round | 01/04/2012 | Defensor Sporting | - | Liverpool | 4:2 | ||||
| 4. Round | 05/04/2012 | Defensor Sporting | - | Peñarol | 0:0 | ||||
| 8. Round | 14/04/2012 | Defensor Sporting | - | Racing | 5:1 | ||||
| 9. Round | 22/04/2012 | CA Cerro | - | Defensor Sporting | 2:3 | ||||
| 10. Round | 29/04/2012 | Defensor Sporting | - | Montevideo Wanderers | 2:1 |
Uruguay