| 4. Round | 22/07/2022 | Mazatlán FC [U20] | - | Atlético San Luis [U20] | 5:0 | ||||
| 8. Round | 11/08/2022 | Gallos Blancos [U20] | - | Atlético San Luis [U20] | 0:3 | ||||
| 10. Round | 21/08/2022 | Atlético San Luis [U20] | - | Deportivo Toluca [U20] | 5:0 | ||||
| 15. Round | 18/09/2022 | Atlético San Luis [U20] | - | CF Pachuca [U20] | 1:3 | ||||
| 17. Round | 01/10/2022 | Atlético San Luis [U20] | - | UANL Tigres [U20] | 2:2 |
Mexico