| 4. Round | 26/09/2010 | Skoda Xanthi | - | PAOK Saloniki | 1:0 | ||||
| 5. Round | 03/10/2010 | AEK Athen | - | Skoda Xanthi | 1:0 |  |
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| 6. Round | 16/10/2010 | Skoda Xanthi | - | Olympiakos Piraeus | 0:3 | ||||
| 10. Round | 13/11/2010 | AO Kerkyra | - | Skoda Xanthi | 1:1 | ||||
| 11. Round | 20/11/2010 | Skoda Xanthi | - | Panserraikos | 2:0 | ||||
| 12. Round | 28/11/2010 | Asteras Tripolis | - | Skoda Xanthi | 1:2 | |
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| 13. Round | 05/12/2010 | Skoda Xanthi | - | Olympiakos Volou | 1:0 | ||||
| 21. Round | 06/02/2011 | Olympiakos Piraeus | - | Skoda Xanthi | 1:0 | ||||
| 22. Round | 13/02/2011 | Skoda Xanthi | - | Atromitos | 3:0 | ||||
| 23. Round | 20/02/2011 | Skoda Xanthi | - | AE Lárissa | 1:1 | ||||
| 24. Round | 26/02/2011 | Iraklis Saloniki | - | Skoda Xanthi | 1:1 | |
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| 25. Round | 05/03/2011 | Skoda Xanthi | - | AO Kerkyra | 2:1 | |
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| 26. Round | 12/03/2011 | Panserraikos | - | Skoda Xanthi | 2:1 | |
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| 30. Round | 17/04/2011 | Skoda Xanthi | - | Aris Saloniki | 1:2 |
Greece