| 1. Round | 28/08/2005 | Apollon Kalamarias | - | OFI Heraklion | 2:1 | ||||
| 2. Round | 11/09/2005 | OFI Heraklion | - | Skoda Xanthi | 1:1 | ||||
| 3. Round | 18/09/2005 | Atromitos | - | OFI Heraklion | 4:0 | ||||
| 4. Round | 25/09/2005 | OFI Heraklion | - | Iraklis Saloniki | 0:1 |  |
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| 10. Round | 20/11/2005 | Panionios GSS | - | OFI Heraklion | 1:1 | ||||
| 12. Round | 04/12/2005 | Akratitos Liosion | - | OFI Heraklion | 1:1 |
Greece