| Group 5 | 15/03/2016 | Independiente del Valle | - | FBC Melgar | 2:0 | ||||
| Group 5 | 14/04/2016 | Colo-Colo | - | Independiente del Valle | 0:0 |  |
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| Round of 16 | 28/04/2016 | Independiente del Valle | - | River Plate | 2:0 | ||||
| Round of 16 | 04/05/2016 | River Plate | - | Independiente del Valle | 1:0 | ||||
| Quarter-finals | 18/05/2016 | Independiente del Valle | - | Pumas UNAM | 2:1 | |
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| Quarter-finals | 25/05/2016 | Pumas UNAM | - | Independiente del Valle | 3:5 pso | ||||
| Semi-finals | 08/07/2016 | Independiente del Valle | - | Boca Juniors | 2:1 |
Ecuador