| 2. Round | 31/07/2021 | FC Mynai | - | FK Oleksandriya | 1:0 | ||||
| 1. Round | 11/08/2021 | Dinamo Kiev | - | FC Mynai | 2:0 | ||||
| 4. Round | 14/08/2021 | Zorya Lugansk | - | FC Mynai | 1:1 | ||||
| 5. Round | 21/08/2021 | NK Veres | - | FC Mynai | 1:0 | ||||
| 6. Round | 29/08/2021 | FC Mynai | - | Shakhtar Donetsk | 1:1 | ||||
| 8. Round | 19/09/2021 | Vorskla Poltava | - | FC Mynai | 2:0 | ||||
| 9. Round | 26/09/2021 | FC Mynai | - | FK Lviv | 1:2 | ||||
| 11. Round | 17/10/2021 | FC Mynai | - | Desna Chernigov | 0:0 | ||||
| 12. Round | 24/10/2021 | Rukh Lviv | - | FC Mynai | 2:2 |  |
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| 13. Round | 01/11/2021 | SK Dnipro-1 | - | FC Mynai | 4:0 | ||||
| 14. Round | 06/11/2021 | FC Mynai | - | FK Mariupol | 0:2 | ||||
| 15. Round | 21/11/2021 | FC Mynai | - | Inhulets Petrove | 2:2 | ||||
| 3. Round | 24/11/2021 | FC Mynai | - | Kolos Kovalivka | 1:1 | ||||
| 16. Round | 27/11/2021 | FC Mynai | - | Dinamo Kiev | 0:2 | ||||
| 17. Round | 05/12/2021 | FK Oleksandriya | - | FC Mynai | 3:0 |
Ukraine