| 6. Round | 06/09/2021 | Las Vegas Lights FC | - | Sacramento Republic | 1:3 | ||||
| 6. Round | 09/09/2021 | Las Vegas Lights FC | - | Oakland Roots | 0:1 | ||||
| 6. Round | 12/09/2021 | Orange County SC | - | Las Vegas Lights FC | 3:0 |  |
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| 6. Round | 16/09/2021 | Phoenix Rising | - | Las Vegas Lights FC | 4:1 | ||||
| 6. Round | 26/09/2021 | Las Vegas Lights FC | - | San Diego Loyal | 2:4 | |
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| 7. Round | 03/10/2021 | Oakland Roots | - | Las Vegas Lights FC | 2:2 | ||||
| 7. Round | 09/10/2021 | Las Vegas Lights FC | - | Los Angeles Galaxy II | 0:1 | ||||
| 7. Round | 14/10/2021 | Tacoma Defiance | - | Las Vegas Lights FC | 0:1 | ||||
| 7. Round | 16/10/2021 | Las Vegas Lights FC | - | Phoenix Rising | 3:6 | ||||
| 7. Round | 24/10/2021 | Orange County SC | - | Las Vegas Lights FC | 2:1 | ||||
| 7. Round | 31/10/2021 | Las Vegas Lights FC | - | Tampa Bay Rowdies | 1:2 |
USA