| 7. Round | 25/09/2022 | Las Vegas Lights FC | - | San Diego Loyal | 1:2 | ||||
| 8. Round | 02/10/2022 | Orange County SC | - | San Diego Loyal | 2:2 |  |
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| 8. Round | 09/10/2022 | San Diego Loyal | - | New Mexico United | 3:3 | |
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| 8. Round | 16/10/2022 | Sacramento Republic | - | San Diego Loyal | 4:0 |
Ghana