| 10. Round | 23/09/2020 | San Luis | - | Santa Cruz | 0:0 | ||||
| 11. Round | 27/09/2020 | Unión San Felipe | - | San Luis | 2:1 | ||||
| 12. Round | 30/09/2020 | San Luis | - | Puerto Montt | 2:0 | ||||
| 16. Round | 27/10/2020 | Unión San Felipe | - | San Luis | 1:1 | ||||
| 17. Round | 04/11/2020 | San Luis | - | CD Magallanes | 0:1 | ||||
| 19. Round | 12/11/2020 | San Luis | - | Cobreloa | 0:1 | ||||
| 23. Round | 05/12/2020 | Puerto Montt | - | San Luis | 5:0 | ||||
| 27. Round | 23/12/2020 | Barnechea | - | San Luis | 2:0 | ||||
| 28. Round | 30/12/2020 | Santa Cruz | - | San Luis | 1:3 | ||||
| 22. Round | 04/01/2021 | San Luis | - | Santiago Morning | 1:1 | ||||
| 29. Round | 12/01/2021 | San Luis | - | Deportes Temuco | 3:0 | ||||
| 30. Round | 17/01/2021 | Deportes Copiapó | - | San Luis | 1:0 |
Chile
Netherlands