| 4. Round | 28/08/2021 | Stade Plabennec | - | FC Lorient B | 1:1 | ||||
| 15. Round | 14/01/2022 | FC Rouen 1899 | - | FC Lorient B | 1:1 | ||||
| 21. Round | 12/03/2022 | SM Caen B | - | FC Lorient B | 1:3 | ||||
| 23. Round | 26/03/2022 | FC Lorient B | - | AS Poissy | 3:0 | ||||
| 24. Round | 09/04/2022 | C'Chartres Football | - | FC Lorient B | 2:5 | ||||
| 25. Round | 16/04/2022 | FC Lorient B | - | Châteaubriant Voltigeurs | 0:0 | ||||
| 26. Round | 23/04/2022 | Vannes OC | - | FC Lorient B | 0:3 | ||||
| 29. Round | 21/05/2022 | FC Lorient B | - | FC Rouen 1899 | 1:1 | ||||
| 30. Round | 28/05/2022 | AS Vitré | - | FC Lorient B | 0:5 |
France